Abstract: In the uncertain environment of entrepreneurship, how to make decisions is a topic worth discussing. Starting from the psychological activities of entrepreneurs, this study explores the influence mechanism of entrepreneurs' heuristic decision logic and collects two groups of samples from China and the United States. Through the structural equation model empirical analysis of 171 samples from China and 116 samples from the United States, it is found that perspective taking and entrepreneurial passion are important antecedents of entrepreneurial decision-making logics, self-efficacy plays a mediating role in the relationship between perspective taking and decision making logics as well as in the relationship between entrepreneurial passion and decision making logics. Through the cross-country test, the research results indicate to have universal significance. This paper extends the research on the formation mechanism of entrepreneur's decision-making logics. The conclusion is helpful for entrepreneurs to scientifically make decisions.