Abstract: Creational and original capacity is the essential requirement of national high-quality development and a strategic choice to cope with international challenges. Based on the related research of creational and original capacity and the basic principle of Bayesian network, this paper constructs the Bayesian network model of the influence mechanism of creational and original capacity. By using mathematical reasoning, algorithm simplification and example analysis, the dynamic change state of diversification, complexity and uncertainty influencing factors of creational and original capacity is simulated and carried out by changing the prior probability of initial node and conditional probability of intermediate node in Bayesian network. The research results show that: the research on creational and original capacity based on Bayesian network not only transforms the theoretical, complex, systematic and structured creational and original capacity into a quantifiable and comparable mathematical problem, but also breaks the traditional single and static limitations of the influence mechanism, and provides an ideal dynamic change process for the influence mechanism of creational and original capacity. The solution provides reference and support for the cultivation, development and promotion of creational and original capacity.