Abstract: Based on the technology-organization-environment (TOE) framework, the digitization configuration reflecting index is designed. Combined with the projection pursuit method, the digitization configuration character of eastern, central and western areas of China are identified by using the sample data from 2011 to 2019; LDA method is used to extract key words to obtain ten themes of three major policies - element, process and application policy; fsQCA method is used to explore the matching policy combination, and the corresponding matching relationship between regional digitization configuration and policy combination is also offered. The four core policies extracted are element and process policies, and the application policies are auxiliary policies. Finally, the priority of policy combination in different regions is determined by using the method of geographic detector. The results show that the implementation effect of policy combination is better than that of single policy. The element policy is high-level policy, and its internal importance order is digital infrastructure, digital technology, digital talents and digital analysis; Process policy is the intermediate policy, the internal order is digital commerce, digital production and digital logistics; Application policy is the preliminary policy, the internal order is digital government, digital industry and digital society.