Abstract: At present, the development of intelligent technology is in full swing, which has reshaped the factor allocation structure and allocation efficiency. As one of the important production factors, has intelligent application improved the human capital mismatch? Using the panel data of 276 prefecture-level cities from 2010 to 2019, the impact of intelligence on human capital mismatch and the path of action are examined. The study found that: intelligent applications can improve the human capital misallocation; this effect is different between different geographical locations and city levels; intelligent applications can improve human capital mismatches in the "intelligent application→increase in average income→human capital flow→Human capital mismatch improvement”and“intelligent application→widening income gap→human capital flow→human capital mismatch improvement” two paths of action; intelligent application can improve local human capital mismatch, but it has a reverse effect on surrounding areas. Therefore, on the basis of following the laws of the market, it is necessary to coordinate the layout of the intelligent industry and focus on promoting intelligent upgrading and transformation.