Abstract: Starting from the interactive demand of S&T service industry and manufacturing industry, it combines the connotation of the S&T service industry and the mechanism interacted with manufacturing upgrade. First of all, the index layer is compared and carding through reviewing a number of documents. Then an evaluation index system for the development level of the S&T service industry has been established taking four dimensions (scale capabilities, technological innovation, service object, and comprehensive potentials) based on the subject service capabilities and the development of some externally-associated supporting industries. Also the panel data of 2007-2016 China 30 provinces is used to measure the level of S&T service industry index and gained comparative analysis of overall and three plates, also regional spatial layout. Moreover some policy proposals are proposed for promoting the development of the S&T service industry in China.