Abstract: Technology transfer is the basis of new products even new industries. It is a critical mechanism of economic growth. How to optimize the policy of technology transfer so as to promote regional technology transfer is an important issue. In view of the divergence in policy systems among different levels of government networks and in regional technological resources in China, this paper examines the configuration effects of policy supply, policy coordination, technology source, organization strength, and self consistency on the effectiveness of technology transfer, as well as the influence of different configurations on it with the data of 160 transfer agents out of four areas as Hubei, Guangdong, Shanghai, Zhejiang, from the perspective of integrative framework. CFA and fsQCA method were applied，and regional technological resources and organizational context were considered. Result shows that: (1) Single conditional element of technology commercialization do not contribute to the necessary conditions for the high efficiency, but policy coordination plays a key role in the producing of high efficiency; (2) None of the resources-based, organizational-based or system-based theoretical perspectives can fully explain the transfer outcome, only a combination of different perspectives can provide a reasonable explanation; (3) Three types of technology commercialization conditions may lead to high efficiency, including the Policy-Supply-Based Agent Capable Model, the Policy-Coordinate-Based Technology Resource Model, and the Policy-Coordinate-Based Self Consistency Model. Different condition combinations represent the multiple ways to realize the high effeciency of technology commercialization. Four kinds of transfer conditions which might lead to low efficiency are also discussed, which all indicates missing of policy condition elements. From the integrative configuration perspective, this paper explores the impact of policy supply and policy coordination on the effectiveness of technology transfer under specific background of resources and organizations. The research findings have important theoretical and practical significance for revealing the implementation path of policy conditions for high efficiency of technology transfer in China.